Moments worth keeping in mind in coming to grips with the Renaissance: 1453: Fall of Constantinople 1455: The War of the Roses breaks out in England 1485: War concludes as the Tudors take over, under King Henry VII 1492. The first of Columbus' voyages. 1494: Savonarola takes over in Florence 1498: Savonarola executed. 1504. Michelangelo completes work on his DAVID. 1510. Hieronymous Bosch paints THE GARDEN OF EARTHLY DELIGHTS 1513. Niccolo Machiavelli puts out THE PRINCE, a study of the means that one must use to control a city-state, expressing a devout hope for the unity of Italy against its foreign oppressors. 1530. The earliest known pictures of instruments recognizable as violins date to this time, in northern Italy. 1598. The earliest known work that could be modern standards be considered an opera is performed in this year, DAFNE, in Florence. 1605. The publication of Cervantes' masterpiece, Don Quixote.