I have mentioned Mayo and her book, STATISTICAL INFERENCE AND SEVERE TESTING before. Here I come back to it to provide you with some fruits of my readings therein. Duhem's problem. Pierre Duhem said that experimental falsification doesn't get us very far in physics because the error that explains the surprising experimental result could invariably have come from any of a number of related postulates. The surprising result only tells us that ONE of them is wrong. "The only thing the experiment teaches us is ... there is at least one error; but, where this error lies is just what it does not tell us." [a 1954 book.] Quine said much the same, though he didn't think the idea restricted to physics. Popper replied, in CONJECTURES AND REFUTATIONS (1962). "We can be reasonably successful in attributing our refutations to definite portions of the theoretical maze. (For we are reasonably successful in this -- a fact which remains inexplicable for one who...